TRUNCATE-TB Steering Committee Meets for the First Time in Singapore
Posted 17 February 2026
The TRUNCATE-TB clinical trial's Trial Steering Committee (TSC) held its inaugural meeting on 11 February 2026 at the National University of Singapore (NUS). Those present included Dr. Gerry Davies (UK), Prof. Charles Gilks (Australia), Prof. Guy Thwaites (UK/Vietnam), Dato' Dr. Hj. Abdul Razak Muttalif (Malaysia) and Dr. Sushil Pandey (Australia). Joining them were chief investigator Prof. Nick Paton (Singapore), Prof. Andrew Nunn (UK) and Dr. Patrick Phillips (UK) from the MRC Clinical Trials Unit, along with other core trial members and collaborators. Trial sites were represented by Dr. Rovina Ruslami (Padjadjaran University, Indonesia) and Prof. Shenjie Tang (Beijing Chest Hospital, China).
Talks centred on the trial protocol and drug regimens, data management and biostatistics, plus questions of trial logistics, organisation and community involvement. The committee is set to meet regularly until the trial wraps up in 2019.
Background on the TRUNCATE-TB Trial
TRUNCATE-TB (Two-month Regimens Using Novel Combinations to Augment Treatment Effectiveness for drug-sensitive Tuberculosis) is a groundbreaking Phase 3 trial exploring shorter TB treatment regimens, with plans to enrol over 1,000 patients across several Asian countries. The study seeks to determine whether a two-month course of novel combination regimens for drug-sensitive TB — followed by re-treating any relapses with a standard six-month course — is non-inferior to the usual six-month treatment plus six-month re-treatment approach.
University College London (UCL) sponsors the trial, with funding from the UK's Medical Research Council (MRC), Wellcome Trust and Department for International Development (DfID), alongside the National Medical Research Council (NMRC) in Singapore. The National University of Singapore (NUS) manages it, and the Singapore Clinical Research Institute (SCRI) coordinates it. TRUNCATE-TB is a flagship project under SPRINT-TB's Theme 3: Clinical Trials.
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This archive page gathers SPRINT-TB's February 2015 coverage of the TRUNCATE-TB trial, from the steering committee's first gathering to an overview of the study's design and funding. Use the monthly links above to move through earlier and later news, or visit the News section for the latest updates from the programme.